abstract：OBJECTIVE:To determine the safety, tolerability, and efficacy of combination gefitinib and methotrexate to treat ectopic pregnancy. METHODS:We performed a phase I, single-arm (nonrandomized), open-label study. Twelve women with ectopic pregnancies were administered methotrexate (50 mg/m, intramuscular) and 250 mg oral...

journal_title：Obstetrics and gynecology

authors： Skubisz MM,Horne AW,Johns TG,Nilsson UW,Duncan WC,Wallace EM,Critchley HOD,Tong S

更新日期：2013-10-01 00:00:00

abstract：:This month, we focus on current research in postpartum hemorrhage. Dr. Rouse discusses five recent publications, and each is concluded with a "bottom line" that is the take-home message. The complete reference for each can be found in on this page, along with direct links to the abstracts. ...

journal_title：Obstetrics and gynecology

authors： Rouse DJ

更新日期：2013-09-01 00:00:00

abstract：OBJECTIVE:To examine the effect of underlying maternal morbidities on the odds of maternal death during delivery hospitalization. METHODS:We used data that linked birth certificates to hospital discharge diagnoses from singleton live births at 22 weeks of gestation or later during 1995-2003 in New York City. Maternal ...

journal_title：Obstetrics and gynecology

authors： Campbell KH,Savitz D,Werner EF,Pettker CM,Goffman D,Chazotte C,Lipkind HS

更新日期：2013-09-01 00:00:00

abstract：OBJECTIVE:To examine the effectiveness of lidocaine spray compared with conventional lidocaine submucosal injection during a loop electrosurgical excision procedure (LEEP). METHODS:Women undergoing LEEP for any degrees of cervical intraepithelial neoplasia were invited to participate. The participants were randomly as...

journal_title：Obstetrics and gynecology

authors： Vanichtantikul A,Charoenkwan K

更新日期：2013-09-01 00:00:00

abstract：BACKGROUND:Atypical hemolytic uremic syndrome (HUS) is a thrombotic microangiopathy often caused by mutations in complement genes. During pregnancy, disease outcome is poor both for mother and fetus. Since 2009, the humanized monoclonal antibody eculizumab has been successfully used in the treatment of atypical HUS in ...

journal_title：Obstetrics and gynecology

authors： Ardissino G,Wally Ossola M,Maria Baffero G,Rigotti A,Cugno M

更新日期：2013-08-01 00:00:00

abstract：BACKGROUND:Approximately 2% of all pregnancies are ectopic; of these, 4% are interstitial or cervical. There exists no clear consensus as to whether surgical or medical management is superior. CASE:We present three cases of advanced nonfallopian tube ectopic pregnancies from 6 to 8 weeks of gestation. Our first two ca...

journal_title：Obstetrics and gynecology

authors： Swank ML,Harken TR,Porto M

更新日期：2013-08-01 00:00:00

abstract：:Single-incision laparoscopy is a minimally invasive technique that decreases the number of operative sites used in traditional laparoscopic surgery to one skin incision, with the potential advantages of improving cosmesis and decreasing postoperative pain. There are limited data to demonstrate the safety and feasibili...

journal_title：Obstetrics and gynecology

authors：

更新日期：2013-08-01 00:00:00

abstract：:This month, we focus on current research in preterm birth prevention. Dr. Andrews discusses recent publications, and each is concluded with a "bottom line" that is the take-home message. The complete reference for each can be found in on this page, along with direct links to the abstracts. ...

journal_title：Obstetrics and gynecology

authors： Andrews WW

更新日期：2013-08-01 00:00:00

abstract：OBJECTIVE:To describe the presenting symptoms of women with depression in two obstetrics and gynecology clinics, determine depression diagnosis frequency, and examine factors associated with depression diagnosis. METHODS:Data were extracted from charts of women screening positive for depression in a clinical trial tes...

journal_title：Obstetrics and gynecology

authors： Cerimele JM,Vanderlip ER,Croicu CA,Melville JL,Russo J,Reed SD,Katon W

更新日期：2013-08-01 00:00:00

abstract：OBJECTIVE:To examine the availability of trial of labor after cesarean delivery (TOLAC) in New Mexico from 1998 to 2012 and maternity care providers' perception of barriers to TOLAC. METHODS:Hospital maternity unit directors were surveyed regarding TOLAC availability from 1998 to 2012. Maternity care providers (obstet...

journal_title：Obstetrics and gynecology

authors： Leeman LM,Beagle M,Espey E,Ogburn T,Skipper B

更新日期：2013-08-01 00:00:00

abstract：OBJECTIVE:To investigate the association between maternal use of sulfamethizole near term and the risk of neonatal jaundice. METHODS:We conducted a nationwide population-based retrospective cohort study using Danish registers. All Danish women giving birth between 1995 and 2007 were included from the Danish Fertility ...

journal_title：Obstetrics and gynecology

authors： Klarskov P,Andersen JT,Jimenez-Solem E,Torp-Pedersen C,Poulsen HE

更新日期：2013-07-01 00:00:00

abstract：OBJECTIVE:To estimate the overall reduction in ovarian cancer risk associated with the use of oral contraceptive pills (OCPs) and whether reduction in risk is affected by specifics of OCP use, such as formulation or duration of use. DATA SOURCES:We searched PubMed, Embase, the Cochrane Database of Systematic Reviews, ...

journal_title：Obstetrics and gynecology

authors： Havrilesky LJ,Moorman PG,Lowery WJ,Gierisch JM,Coeytaux RR,Urrutia RP,Dinan M,McBroom AJ,Hasselblad V,Sanders GD,Myers ER

更新日期：2013-07-01 00:00:00

abstract：OBJECTIVE:To evaluate whether early oral intake after cesarean delivery has an effect on gastrointestinal outcomes during postpartum recovery. DATA SOURCES:Electronic searches of published studies between 1980 and 2011 were conducted using PubMed, Medline, CINAHL, ClinicalTrials.gov, and Airiti databases. METHODS OF ...

journal_title：Obstetrics and gynecology

authors： Hsu YY,Hung HY,Chang SC,Chang YJ

更新日期：2013-06-01 00:00:00

abstract：OBJECTIVE:To compare the prevalence of large-for-gestational-age (LGA) newborns across categories of body mass index (BMI) in five racial and ethnic groups. METHODS:This cohort study examined 7,468 women with gestational diabetes mellitus (GDM) who delivered a live newborn between 1995 and 2006 at Kaiser Permanente No...

journal_title：Obstetrics and gynecology

authors： Sridhar SB,Ferrara A,Ehrlich SF,Brown SD,Hedderson MM

更新日期：2013-06-01 00:00:00

abstract：OBJECTIVE:To estimate determinants of and outcomes associated with activity restriction among women with a short cervix. METHODS:This was a secondary analysis of a randomized trial of 17-α hydroxyprogesterone caproate for prevention of preterm birth among nulliparous women with singleton gestations and cervices less t...

journal_title：Obstetrics and gynecology

authors： Grobman WA,Gilbert SA,Iams JD,Spong CY,Saade G,Mercer BM,Tita ATN,Rouse DJ,Sorokin Y,Leveno KJ,Tolosa JE,Thorp JM,Caritis SN,Peter Van Dorsten J,Eunice Kennedy Shriver National Institute of Child Health and Human Development

更新日期：2013-06-01 00:00:00

abstract：OBJECTIVE:To estimate the rates of early neonatal and maternal complications in a consecutive series of successful Kielland's rotational forceps deliveries. METHODS:This was a retrospective cohort study of consecutive cases of successful rotational forceps deliveries performed in singleton pregnancies at 36 weeks of g...

journal_title：Obstetrics and gynecology

authors： Stock SJ,Josephs K,Farquharson S,Love C,Cooper SE,Kissack C,Akolekar R,Norman JE,Denison FC

更新日期：2013-05-01 00:00:00

abstract：OBJECTIVE:Many U.S. health care providers remain reluctant to prescribe intrauterine devices (IUDs) to teenagers as a result of concerns about serious complications. This study examined whether 15-19-year-old IUD users were more likely to experience complications, failure, or early discontinuation than adult users aged...

journal_title：Obstetrics and gynecology

authors： Berenson AB,Tan A,Hirth JM,Wilkinson GS

更新日期：2013-05-01 00:00:00

abstract：:For certain medical conditions, available data and expert opinion support optimal timing of delivery in the late-preterm or early-term period for improved neonatal and infant outcomes. However, for nonmedically indicated early-term deliveries such an improvement has not been demonstrated. Morbidity and mortality rates...

journal_title：Obstetrics and gynecology

authors：

更新日期：2013-04-01 00:00:00

abstract：OBJECTIVE:To estimate whether the timing of bladder emptying affects focal myometrial contraction development and image adequacy. METHODS:Women at 14 0/7-32 0/7 weeks of gestation undergoing a transvaginal ultrasound examination from January 1, 2012, to September 1, 2012, were eligible for this blinded randomized cont...

journal_title：Obstetrics and gynecology

authors： Schnettler W,March M,Hacker MR,Modest AM,Rodriguez D

更新日期：2013-04-01 00:00:00

abstract：OBJECTIVE:Emerging data suggest that oophorectomy at the time of hysterectomy for benign indications may increase long-term morbidity and mortality. We performed a population-based analysis to estimate the rates of oophorectomy in women undergoing hysterectomy for benign indications. METHODS:The Perspective database w...

journal_title：Obstetrics and gynecology

authors： Perera HK,Ananth CV,Richards CA,Neugut AI,Lewin SN,Lu YS,Herzog TJ,Hershman DL,Wright JD

更新日期：2013-04-01 00:00:00

abstract：OBJECTIVE:To estimate the effectiveness against early-onset group B streptococcal (GBS) disease of intrapartum antibiotic prophylaxis among term and preterm deliveries, deliveries with fewer than 4 hours of antibiotics, and deliveries receiving clindamycin regimens. METHODS:We performed a secondary analysis of the Bir...

journal_title：Obstetrics and gynecology

authors： Fairlie T,Zell ER,Schrag S

更新日期：2013-03-01 00:00:00

abstract：BACKGROUND:Vulvodynia is a complex and multifactorial clinical condition with severe pain that occurs in the absence of visible infectious, inflammatory, neoplastic, or neurological findings. CASE:A 35-year-old woman with 3 years of dysesthetic vulvodynia tried conventional and interventional medical treatment with in...

journal_title：Obstetrics and gynecology

authors： De Andres J,Sanchis-Lopez N,Asensio-Samper JM,Fabregat-Cid G,Dolz VM

更新日期：2013-02-01 00:00:00

abstract：BACKGROUND:Placental site trophoblastic tumor is a rare subtype of gestational trophoblastic neoplasia affecting women of reproductive age. The preferred method of treatment is surgical resection. CASE:A 33-year-old woman, gravida 3 para 1111, was incidentally diagnosed with placental site trophoblastic tumor during a...

journal_title：Obstetrics and gynecology

authors： Taylor JS,Viera L,Caputo TA,Chan J,Frey MK,Gupta D,Kligman I

更新日期：2013-02-01 00:00:00

abstract：BACKGROUND:Extensive bowel resection may lead to a state of inadequate nutrient absorption and malnutrition known as short bowel syndrome. Deficiencies in fat-soluble vitamins may occur from this condition, with sequelae such as a bleeding diathesis. Maternal vitamin deficiencies also have been associated with fetal an...

journal_title：Obstetrics and gynecology

authors： Grabosch S,Pennycook J,Pakravan A,Mostello D

更新日期：2013-02-01 00:00:00

abstract：OBJECTIVE:To estimate whether first-trimester exposure to nitrofurantoin is associated with increased malformation rates and, secondarily, to estimate whether exposure to nitrofurantoin is associated with increased rates of negative pregnancy outcomes and perinatal complications. METHODS:We conducted a population-base...

journal_title：Obstetrics and gynecology

authors： Nordeng H,Lupattelli A,Romøren M,Koren G

更新日期：2013-02-01 00:00:00

abstract：OBJECTIVE:To estimate variation across hospitals in the rate of postpartum sterilization. METHODS:All hospitals with deliveries in California and Texas in 2009 were included. Proportion of live singleton deliveries with postpartum sterilization was calculated by hospital, insurance status (Medicaid compared with priva...

journal_title：Obstetrics and gynecology

authors： Potter JE,Stevenson AJ,White K,Hopkins K,Grossman D

更新日期：2013-01-01 00:00:00

abstract：OBJECTIVE:To estimate the relationship between hormonal parameters of diminished ovarian reserve and the incidence of aneuploid blastocysts. METHODS:This prospective cohort trial was performed in a private in vitro fertilization clinic. Three hundred seventy-two patients underwent in vitro fertilization with blastocys...

journal_title：Obstetrics and gynecology

authors： Katz-Jaffe MG,Surrey ES,Minjarez DA,Gustofson RL,Stevens JM,Schoolcraft WB

更新日期：2013-01-01 00:00:00

abstract：:The optimal timing for clamping the umbilical cord after birth has been a subject of controversy and debate. Although many randomized controlled trials in term and preterm infants have evaluated the benefits of delayed umbilical cord clamping versus immediate umbilical cord clamping, the ideal timing for cord clamping...

journal_title：Obstetrics and gynecology

authors： Committee on Obstetric Practice, American College of Obstetricians and Gynecologists.

更新日期：2012-12-01 00:00:00

abstract：:The postpartum dose of Rh immune globulin varies according to an individual laboratory estimation of fetal red blood cells in each mother's peripheral blood. In the United States, a four-step procedure determines the postpartum dose (number of vials of 300 micrograms; 1,500 international units) of Rh immune globulin (...

journal_title：Obstetrics and gynecology

authors： Sandler SG,Gottschall JL

更新日期：2012-12-01 00:00:00

abstract：OBJECTIVE:To present tactics for optimizing outpatient vaginal hysterectomy and describe perioperative outcomes in a large consecutive case series. METHODS:This is a descriptive study and review of clinical outcomes in 1,071 patients selected to undergo vaginal hysterectomy for benign indications from 2000 to 2010. Th...

journal_title：Obstetrics and gynecology

authors： Zakaria MA,Levy BS

更新日期：2012-12-01 00:00:00

abstract：OBJECTIVES:To compare patient satisfaction and exclusive breastfeeding rates for patients discharged from the hospital on postcesarean day 1 (next day) or day 2. METHODS:Healthy women admitted for planned cesarean delivery were randomized to day 1 or day 2 discharge. Postoperative assessment for suitability for discha...

journal_title：Obstetrics and gynecology

authors： Tan PC,Norazilah MJ,Omar SZ

更新日期：2012-12-01 00:00:00

abstract：:The incidence of cervical cancer in the United States has decreased more than 50% in the past 30 years because of widespread screening with cervical cytology. In 1975, the rate was 14.8 per 100,000 women. By 2008, it had been reduced to 6.6 per 100,000 women. Mortality from the disease has undergone a similar decrease...

journal_title：Obstetrics and gynecology

authors： Committee on Practice Bulletins—Gynecology.

更新日期：2012-11-01 00:00:00

abstract：OBJECTIVE:All national organizations now recommend that women be screened for cervical cancer beginning at age 21 years, regardless of age of sexual initiation; however, studies have shown that providers continue to screen much earlier than recommended. Two federal cancer surveillance systems were used to quantify the ...

journal_title：Obstetrics and gynecology

authors： Benard VB,Watson M,Castle PE,Saraiya M

更新日期：2012-11-01 00:00:00

abstract：OBJECTIVE:To estimate the incidence of surgical-site infection with use of chlorhexidine-alcohol compared with povidone-iodine among women undergoing cesarean deliveries. METHODS:This was a retrospective cohort review of 1,000 consecutive cases in women who underwent cesarean delivery over a 1-year interval. The prima...

journal_title：Obstetrics and gynecology

authors： Menderes G,Athar Ali N,Aagaard K,Sangi-Haghpeykar H

更新日期：2012-11-01 00:00:00

abstract：:Most reported associations in observational clinical research are false, and the minority of associations that are true are often exaggerated. This credibility problem has many causes, including the failure of authors, reviewers, and editors to recognize the inherent limitations of these studies. This issue is especia...

journal_title：Obstetrics and gynecology

authors： Grimes DA,Schulz KF

更新日期：2012-10-01 00:00:00

abstract：OBJECTIVE:To assess the relationship between preeclampsia or eclampsia and stroke, myocardial infarction (MI), subsequent cardiovascular outcomes, and long-term survival. METHODS:Using the Myocardial Infarction Data Acquisition System in New Jersey (1994-2009), we analyzed cardiovascular outcomes in women with and wit...

journal_title：Obstetrics and gynecology

authors： Gastrich MD,Gandhi SK,Pantazopoulos J,Zang EA,Cosgrove NM,Cabrera J,Sedjro JE,Bachmann G,Kostis JB,Myocardial Infarction Data Acquisition System (MIDAS 17) Study Group.

更新日期：2012-10-01 00:00:00

abstract：OBJECTIVE:To estimate the incidence of gestational diabetes mellitus (GDM) according to The International Association of the Diabetes and Pregnancy Study Groups (IADPSG) criteria and the pregnancy complications in women fulfilling these criteria but who are not considered diabetic according to the Canadian Diabetes Ass...

journal_title：Obstetrics and gynecology

authors： Bodmer-Roy S,Morin L,Cousineau J,Rey E

更新日期：2012-10-01 00:00:00

abstract：OBJECTIVE:To assess the effectiveness of intrauterine local anesthesia in reducing pain associated with outpatient gynecologic procedures. DATA SOURCES:We searched online databases PubMed or MEDLINE, Embase, Google Scholar, and Clinicaltrials.gov and hand-searched reference lists from reviews evaluating pain-control m...

journal_title：Obstetrics and gynecology

authors： Mercier RJ,Zerden ML

更新日期：2012-09-01 00:00:00

abstract：OBJECTIVE:To compare surgical outcome and quality of life of robot-assisted laparoscopic hysterectomy with conventional laparoscopic hysterectomy. METHODS:For this controlled clinical trial, patients with benign indications for hysterectomy were randomized to receive either a robotic (robotic group) or conventional la...

journal_title：Obstetrics and gynecology

authors： Sarlos D,Kots L,Stevanovic N,von Felten S,Schär G

更新日期：2012-09-01 00:00:00

abstract：OBJECTIVE:To determine predictors of fistula repair outcomes 3 months postsurgery. METHODS:We conducted a multicountry prospective cohort study between 2007 and 2010. Outcomes, measured 3 months postsurgery, included fistula closure and residual incontinence in women with a closed fistula. Potential predictors include...

journal_title：Obstetrics and gynecology

authors： Barone MA,Frajzyngier V,Ruminjo J,Asiimwe F,Barry TH,Bello A,Danladi D,Ganda SO,Idris S,Inoussa M,Lynch M,Mussell F,Podder DC

更新日期：2012-09-01 00:00:00